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Our Solution

Newrotex’s initial product is SilkAxons® luminal spider silk fibres that can be implanted into a vein or hollow conduit to allow effective long-length nerve repairs.

There exists strong preclinical data for silk. Multiple animal trials show that silk fibres from spiders exhibit equivalent or superior axonal regeneration compared to autografts. Our first-in-human clinical trial preliminary data also supports this. 

Harvested from Nephila spiders our luminal silk fibres can be implanted inside a vein or hollow conduit to support nerve re-growth. These silk fibres mimic the natural ‘Bands of Büngner’, providing an excellent scaffold for nerve regeneration.

Our first product is a 10cm implant which can be used for large nerve gap repairs (or shortened for use in smaller gaps). 

The Newrotex Nerve Conduit

Our secondary product is an off-the-shelf silk conduit containing SilkAxons®. This product provides surgical ease, negating the need to thread the implant through a vein. The simplicity of the surgical techniques required to implant this off-the-shelf device result in significant cost savings and improve the speed to nerve repair. This will in turn improve patient outcomes as there is a direct correlation between efficacy and time to treatment.  

 

Our solution allows the intraluminal distribution of fibres without excessive material for the regenerating nerve to have to break down. This dramatically improves the efficacy when performing long-gap peripheral nerve repairs. 

Our luminal silk fibres are available in any length or diameter to match the damaged nerve. They can be used to repair small nerves, such as with oral and maxillofacial surgery (OMFS) and urology, or large nerves as found in cases of trauma, cancer resection, and breast neurotisation. 

Finally, Newrotex luminal silk fibres are easily combined with existing techniques and regulatory-approved devices expanding its indications for use.

Benefits of Newrotex Nerve Solutions

There are many benefits to using our filled silk tubes for axon regrowth and peripheral nerve repair, including but not limited to the following:

Completely biodegradable

Capable of large gap repair (according to pre-clinical data)

Reduces surgery times and overall procedure costs

Excellent scaffold for nerve regeneration

Length and diameter can be adjusted to match the damaged nerve

Greatly shortened recovery time reduces socioeconomic burden

Inexpensive and easy to store, package, and delivery

Readily available for use in all hospitals by any surgical speciality

Mitigates unforeseen costs, including from complications with nerve autograft procedures

Trials for Newrotex Silk Biomaterials

There is strong preclinical data for silk applications from studies showing both fibres and conduits made from silk to be effective for peripheral nerve repair. Newrotex has conducted animal trials and a first-in-human clinical study on large-gap nerve repair.

Read the Trials page for more details on the preclinical data and Newrotex’s clinical trials.

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Our Vision

Newrotex aims to improve aspects of surgical nerve repair for all parties involved in the process.

Patients

For patients, it means improving outcomes and eliminating the need for harmful autograft procedures.

Surgeons

For surgeons, it means fewer complications by employing repeatable, simple techniques and shorter operating times.

Hospitals & Buyers

For hospitals and national buyers, it means reducing the costs associated with patient morbidity, theatre usage, storage, and supply.

We strive to use our silk technology to help patients suffering nerve injuries due to trauma, cancer surgery, as well as those undergoing breast reconstruction, oral and maxillofacial surgery (OMFS), and urological procedures.

Learn more about our products, facilities, and key people on our About Us page.

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We collaborate with different companies

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